Drug Information

Drug General Information
Drug ID
D08XBF
Former ID
DIB011609
Drug Name
AMEP
Drug Type
Small molecular drug
Indication Melanoma [ICD9: 172; ICD10:C43] Phase 1 [551212]
Company
BioAlliance Pharma SA
Structure
Download
2D MOL

3D MOL
Formula
CH6NO3P
Canonical SMILES
C(N)P(=O)(O)O
InChI
1S/CH6NO3P/c2-1-6(3,4)5/h1-2H2,(H2,3,4,5)
InChIKey
MGRVRXRGTBOSHW-UHFFFAOYSA-N
PubChem Compound ID
14017
PubChem Substance ID
13216, 89426, 3141281, 6127927, 8160553, 14717686, 14915975, 24775906, 24846165, 24859469, 24890431, 24897376, 29282112, 32733221, 50067804, 57328406, 77687962, 85083685, 87562562, 88832842, 103220350, 104222320, 104333338, 104895938, 117531827, 125328959, 125565058, 126690672, 128593059, 134979273, 137008746, 142087985, 152186921, 160782920, 162091552, 162111879, 162272016, 162760597, 163563828, 163566928, 164806396, 175422682, 176317305, 184535542, 186015277, 187071935, 198984435, 202556556, 204432300, 223389561
Target and Pathway
Target(s) Integrin alpha-V/beta-3 Target Info Modulator
Integrin alpha-5/beta-1 Target Info Modulator
KEGG Pathway Phagosome
PI3K-Akt signaling pathway
Focal adhesion
ECM-receptor interaction
Hematopoietic cell lineage
Regulation of actin cytoskeleton
Bacterial invasion of epithelial cells
Shigellosis
Pertussis
Proteoglycans in cancer
MicroRNAs in cancer
Hypertrophic cardiomyopathy (HCM)
Arrhythmogenic right ventricular cardiomyopathy (ARVC)
Dilated cardiomyopathy
Reactome Elastic fibre formation
Fibronectin matrix formation
Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Cell surface interactions at the vascular wall
Basigin interactions
Molecules associated with elastic fibres
Integrin cell surface interactions
Laminin interactions
Syndecan interactions
ECM proteoglycans
Other semaphorin interactions
Localization of the PINCH-ILK-PARVIN complex to focal adhesions
CHL1 interactions
RHO GTPases Activate Formins
WikiPathways Focal Adhesion
Extracellular matrix organization
Elastic fibre formation
Arrhythmogenic Right Ventricular Cardiomyopathy
Integrin-mediated Cell Adhesion
L1CAM interactions
Integrin cell surface interactions
Cell surface interactions at the vascular wall
References
Ref 551212Pre-EMP-tive strike against GBM. SciBX 7(14); doi:10.1038/scibx.2014.389. April 10 2014

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