Drug General Information
Drug ID	D0N2GQ
Former ID	DIB007332
Drug Name	ATI-0917
Synonyms	FB-636
Indication	Human immunodeficiency virus infection [ICD9: 279.3; ICD10:B20-B26]		Phase 1	[530051]
Company	The Procter & Gamble Co
Structure		Download 2D MOL 3D MOL
Canonical SMILES	c1(NC(=O)OC(C)C)cc(ccc1)Cl
CAS Number	CAS 101-21-3
Target and Pathway
Target(s)	HIV REV protein	Target Info	Inhibitor	[530051]
Reactome	Uncoating of the HIV Virion
	Budding and maturation of HIV virion
	Integration of provirus
	Early Phase of HIV Life Cycle
	Minus-strand DNA synthesis
	Plus-strand DNA synthesis
	2-LTR circle formation
	Binding and entry of HIV virion
	Assembly Of The HIV Virion
	Integration of viral DNA into host genomic DNA
	Autointegration results in viral DNA circles
	APOBEC3G mediated resistance to HIV-1 infection
	Vpr-mediated nuclear import of PICs
WikiPathways	Host Interactions of HIV factors
	HIV Life Cycle
References
Ref 530051	Antiretroviral drugs in development. A report from HIV DART 2008: Frontiers in Drug Development for Antiretroviral Therapies, 9-12 December 2008, Rio Grande, Puerto Rico. Expert Opin Investig Drugs. 2009 Apr;18(4):549-53.
Ref 530051	Antiretroviral drugs in development. A report from HIV DART 2008: Frontiers in Drug Development for Antiretroviral Therapies, 9-12 December 2008, Rio Grande, Puerto Rico. Expert Opin Investig Drugs. 2009 Apr;18(4):549-53.

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