Drug Information
Drug General Information | |||||
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Drug ID |
D0LF1U
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Former ID |
DCL000422
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Drug Name |
Flavopiridol
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Synonyms |
FLAVO; Flavopiridol; Alvocidib [INN]; Flavopiridol hydrochloride; L 868275; HMR-1275; L-868275; L86-8275; HMR-1275, Alvocidib, L868275, Flavopiridol; (-)-cis-5,7-Dihydroxy-2-(2-chlorophenyl)-8-(4-(3-hydroxy-1-methyl)piperidinyl)-4H-1-benzopyran-4-one; 2-(2-CHLORO-PHENYL)-5,7-DIHYDROXY-8-(3-HYDROXY-1-METHYL-PIPERIDIN-4-YL)-4H-BENZOPYRAN-4-ONE; 2-(2-chlorophenyl)-5,7-dihydroxy-8-[(3S,4R)-3-hydroxy-1-methylpiperidin-4-yl]chromen-4-one
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Drug Type |
Small molecular drug
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Company |
Sanofi-Aventis
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Structure |
Download2D MOL |
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Formula |
C21H20ClNO5
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InChI |
InChI=1S/C21H20ClNO5/c1-23-7-6-12(17(27)10-23)19-14(24)8-15(25)20-16(26)9-18(28-21(19)20)11-4-2-3-5-13(11)22/h2-5,8-9,12,17,24-25,27H,6-7,10H2,1H3/t12-,17+/m0/s1
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InChIKey |
BIIVYFLTOXDAOV-YVEFUNNKSA-N
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CAS Number |
CAS 131740-09-5
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PubChem Compound ID | |||||
PubChem Substance ID |
606623, 830646, 837792, 7886735, 8035270, 11041362, 14757147, 39320467, 46391640, 46391762, 46507266, 49854007, 50064452, 51029203, 53790160, 57359202, 85177022, 99437041, 104234154, 113870851, 124757102, 125163906, 126671493, 126731324, 127338259, 127338260, 127338261, 127338262, 127338263, 131480733, 134338802, 135064370, 135626623, 136085824, 136367366, 136920327, 137002692, 142106966, 152258050, 160646888, 160966614, 162011554, 164786749, 172818888, 172913786, 175437711, 176236286, 177748773, 178102307, 180371632
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Target and Pathway | |||||
Target(s) | Cyclin-dependent kinase | Target Info | Inhibitor | [549823] | |
Myophosphorylase | Target Info | Inhibitor | [549823] | ||
References | |||||
Ref 537114 | Emerging therapies for multiple myeloma. Expert Opin Emerg Drugs. 2009 Mar;14(1):99-127. | ||||
Ref 541024 | (http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5680). |
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