Drug General Information
Drug ID
D0XW6Y
Former ID
DIB004474
Drug Name
S-38093
Synonyms
S-41150; S-38471-1; S-750-1; Histamine H3 antagonists (sleep/cognitive disorders), Servier
Indication Alzheimer disease [ICD9: 331; ICD10:G30] Phase 2 [549097]
Company
Servier
Structure
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2D MOL

3D MOL

Canonical SMILES
C1CCN2C(C1)CN(CC2)CCCCOc1ccc(cc1)C(=O)c1ccc(cc1)/C(=N/O<br />)/C
Target and Pathway
Target(s) Histamine H3 receptor Target Info Antagonist [549954]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Histamine receptors
G alpha (i) signalling events
WikiPathways Monoamine Transport
GPCRs, Class A Rhodopsin-like
GPCR ligand binding
GPCR downstream signaling
References
Ref 549097Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800032202)
Ref 549954Histamine H3 Receptors and Sleep-Wake Regulation. JPET January 2011 vol. 336 no. 1 17-23.

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