Drug General Information
Drug ID
D0B2JL
Former ID
DIB001873
Drug Name
JWB-1-84-1
Synonyms
Choline analogs (neurodegenerative diseases); Choline analogs (neurodegenerative diseases), Medical College of Georgia; JWB-1-84-1; JWB-1-B4-1
Indication Neurological disease [ICD9: 338, 338.2, 410, 782.3,780; ICD10:I21, I22, R52, R52.1-R52.2, R60.9, G89] Investigative [543844]
Company
Medical College of Georgia
Structure
Download
2D MOL

3D MOL

Canonical SMILES
c1ccc(cn1)CN1CCN(CC1)CCO.Cl.Cl.Cl
CAS Number
CAS 1-84-1
Target and Pathway
Target(s) Acetylcholine receptor Target Info Modulator [543844]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Muscarinic acetylcholine receptors
Acetylcholine regulates insulin secretion
Highly sodium permeable acetylcholine nicotinic receptors
Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
WikiPathways Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell
References
Ref 543844(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 467).
Ref 543844(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 467).

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