Drug Information

Drug General Information
Drug ID
D0D7EK
Former ID
DIB012766
Drug Name
TPI-1361-17
Synonyms
MCH1 receptor antagonist (obesity), Mixture Sciences
Drug Type
Small molecular drug
Indication Obesity [ICD9: 278; ICD10:E66] Investigative [538806]
Company
Mixture Sciences Inc
Structure
Download
2D MOL

3D MOL
Formula
C25H35FN6S
InChI
InChI=1S/C25H35FN6S/c1-19(16-29-17-21-7-3-2-4-8-21)32-18-23(11-6-13-30-24(27)28)31(25(32)33)14-12-20-9-5-10-22(26)15-20/h2-5,7-10,15,19,23,29H,6,11-14,16-18H2,1H3,(H4,27,28,30)/t19-,23-/m0/s1
InChIKey
DSJVYEAOYVHUJW-CVDCTZTESA-N
PubChem Compound ID
11305934
PubChem Substance ID
16394435, 24737176, 42385320, 78758331, 135261560, 135651272, 141827793, 163326676, 163340567, 229926534, 248688905
Target and Pathway
Target(s) Melanin-concentrating hormone receptor 1 Target Info Antagonist [543715]
KEGG Pathway Neuroactive ligand-receptor interaction
Reactome Peptide ligand-binding receptors
G alpha (q) signalling events
G alpha (i) signalling events
WikiPathways GPCRs, Class A Rhodopsin-like
Gastrin-CREB signalling pathway via PKC and MAPK
GPCR ligand binding
GPCR downstream signaling
References
Ref 538806(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1315).
Ref 543715(http://www.guidetopharmacology.org/) Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 280).

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