Drug General Information
Drug ID
D0FC8O
Former ID
DIB001493
Drug Name
DWP-05195
Synonyms
DWJ-204; DWP-0519
Indication Neuropathic pain [ICD9: 356.0, 356.8; ICD10:G64, G90.0] Phase 2 [523840]
Company
Daewoong Pharmaceutical Co Ltd
Target and Pathway
Target(s) Vanilloid receptor 1 Target Info Antagonist [549736]
KEGG Pathway Neuroactive ligand-receptor interaction
Inflammatory mediator regulation of TRP channels
NetPath Pathway IL2 Signaling Pathway
Pathway Interaction Database Trk receptor signaling mediated by the MAPK pathway
Trk receptor signaling mediated by PI3K and PLC-gamma
Reactome TRP channels
References
Ref 523840ClinicalTrials.gov (NCT01557010) Evaluate the Efficacy and Safety of DWP05195 in Subjects With Post-Herpetic Neuralgia. U.S. National Institutes of Health.
Ref 549736TRPV1 Antagonists as Analgesic Agents. The Open Pain Journal, 2013, 6, (Suppl 1: M11), 108-118 .

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