Drug Information

Drug General Information
Drug ID
D01WMW
Former ID
DNCL001799
Drug Name
RG7232
Indication Dyslipidaemias [ICD9: 272; ICD10:E78] Investigative [533320]
Company
Roche
Target and Pathway
Target(s) ATP-binding cassette, sub-family A, member 1 Target Info Modulator [533320]
KEGG Pathway ABC transporters
Fat digestion and absorption
NetPath Pathway Leptin Signaling Pathway
Pathway Interaction Database RXR and RAR heterodimerization with other nuclear receptor
Reactome HDL-mediated lipid transport
PPARA activates gene expression
WikiPathways Statin Pathway
Nuclear Receptors in Lipid Metabolism and Toxicity
Regulation of Lipid Metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Lipid digestion, mobilization, and transport
SREBF and miR33 in cholesterol and lipid homeostasis
Folate Metabolism
Vitamin B12 Metabolism
Selenium Micronutrient Network
References
Ref 533320Analysis of "On/Off" Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):465-73.
Ref 533320Analysis of "On/Off" Kinetics of a CETP Inhibitor Using a Mechanistic Model of Lipoprotein Metabolism and Kinetics. CPT Pharmacometrics Syst Pharmacol. 2015 Aug;4(8):465-73.

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