Drug General Information
Drug ID	D0A3CL
Former ID	DIB001791
Drug Name	AZD1979
Indication	Obesity [ICD9: 278; ICD10:E66]		Phase 1	[524658]
Structure		Download 2D MOL 3D MOL
Target and Pathway
Target(s)	Melanin-concentrating hormone receptor 1	Target Info	Modulator	[550345]
KEGG Pathway	Neuroactive ligand-receptor interaction
Reactome	Peptide ligand-binding receptors
	G alpha (q) signalling events
	G alpha (i) signalling events
WikiPathways	GPCRs, Class A Rhodopsin-like
	Gastrin-CREB signalling pathway via PKC and MAPK
	GPCR ligand binding
	GPCR downstream signaling
References
Ref 524658	ClinicalTrials.gov (NCT02072993) A First Time in Man Study to Assess the Safety, Tolerability and Pharmacokinetics of AZD1979 in Healthy Males. U.S. National Institutes of Health.
Ref 550345	Phase I clinical trial of AZD1979 for treating obesity. AstraZeneca plc

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