| Target Validation Information | |||||
|---|---|---|---|---|---|
| Target ID | T38200 | ||||
| Target Name | GABA transporter-3 | ||||
| Target Type | Research |
||||
| Drug Potency against Target | 4-Hydroxy-piperidine-3-carboxylic acid | Drug Info | IC50 = 11000 nM | [533544] | |
| 2,4-Diamino-butyric acid(GABA) | Drug Info | IC50 = 2000 nM | [533404] | ||
| References | |||||
| Ref 533544 | J Med Chem. 1982 Oct;25(10):1157-62.Hydroxy- and amino-substituted piperidinecarboxylic acids as gamma-aminobutyric acid agonists and uptake inhibitors. | ||||
| Ref 533404 | J Med Chem. 1986 Feb;29(2):224-9.Glycine antagonists. Synthesis, structure, and biological effects of some bicyclic 5-isoxazolol zwitterions. | ||||
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