TTD | Expression Details

Target General Information
Target ID	T09538
Target Name	Alkaline phosphatase tissue-nonspecific
Synonyms	AP-TNAP; Liver/bone/kidney isozyme; TNSALP; ALPL
Target Type	Successful
Gene Name	ALPL
Biochemical Class	Phosphoric monoester hydrolases
UniProt ID	PPBT_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease	Colon cancer
Example drug	Levamisole			Withdrawn from market	[551871], [1572592]
Tissue	Colon tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual	Fold-change: -0.15 Z-score: -0.79 P-value: 4.67E-13
Level of differential expression between the patients in the disease section of the tissue and the patients in the normal section of the tissue adjacent to the disease section	Fold-change: 0.02 Z-score: 0.09 P-value: 8.91E-02
Target gene expression profiles of the patients in the disease section of the tissue Target gene expression profiles of the patients in the normal section of the tissue adjacent to the disease section Target gene expression profiles in the tissue of healthy individual Download target gene expression data of the patients in the disease section of the tissue Download target gene expression data of the patients in the normal section of the tissue adjacent to the disease section Download target gene expression data in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Download the Expression Profile (Genomics. 86(2):127-41, 2005)
Reference
Ref 551871	Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 1572592	NCBI GEO: archive for functional genomics data sets--update.

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