Target General Information
Target ID T19433
Target Name Glutathione S-transferase
Synonyms GST class-alpha; Glutathione-S-transferase; HPGDS
Target Type Successful
Gene Name HPGDS
Biochemical Class Intramolecular oxidoreductases
UniProt ID HPGDS_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Alzheimer's disease
Example drug HF-0220 Phase 2 [521861], [1572592]
Tissue Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 0.34
Z-score: 0.71
P-value: 1.63E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 521861ClinicalTrials.gov (NCT00357357) European Study of HF0220 in Mild to Moderate Alzheimer's Disease Patients. U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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