Target General Information
Target ID T21945
Target Name Norepinephrine transporter
Synonyms NET; Norepinephrine transporter; SLC6A2
Target Type Successful
Gene Name SLC6A2
Biochemical Class Neurotransmitter:sodium symporter
UniProt ID SC6A2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Depression
Example drug Trimipramine Approved [551871], [1572592]
Tissue Pre-frontal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 7.02E-03
Z-score: 0.07
P-value: 7.05E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 551871Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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