Target expression details
Target General Information | |||||
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Target ID | T27889 | ||||
Target Name | Angiotensin-converting enzyme 2 | ||||
Synonyms | ACEH; ACErelated carboxypeptidase; Angiotensinconverting enzyme 2; Angiotensinconverting enzyme homolog; Metalloprotease MPROT15; Processed angiotensinconverting enzyme 2; ACE2 | ||||
Target Type | Clinical Trial | ||||
Gene Name | ACE2 | ||||
Biochemical Class | Peptidase | ||||
UniProt ID | ACE2_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Type 2 diabetes | ||||
Example drug | MLN4760 | Discontinued in Phase 1 | [542794], [547469], [1572592] | ||
Tissue | Liver tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.40 Z-score: 1.10 P-value: 3.93E-02 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
Reference | |||||
Ref 547469 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800016663) |
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