Target General Information
Target ID T40459
Target Name Interleukin-13 receptor alpha-2
Synonyms IL-13R alpha-2 chain; Interleukin-13 binding protein; IL13RA2
Target Type Clinical Trial
Gene Name IL13RA2
Biochemical Class Cytokine receptor
UniProt ID I13R2_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Glioma
Example drug ICT-107 Phase 2 [523325], [1572592]
Tissue Brainstem tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 2.46
Z-score: 1.00
P-value: 4.40E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Disease Glioma
Example drug ICT-107 Phase 2 [523325], [1572592]
Tissue White matter
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 4.14
Z-score: 2.11
P-value: 5.77E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 523325ClinicalTrials.gov (NCT01280552) A Study of ICT-107 Immunotherapy in Glioblastoma Multiforme (GBM). U.S. National Institutes of Health.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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