Target General Information
Target ID T46642
Target Name 5-lipoxygenase activating protein
Synonyms FLAP; MK-886-binding protein; ALOX5AP
Target Type Discontinued
Gene Name ALOX5AP
Biochemical Class Membrane-associated metabolism proteins
UniProt ID AL5AP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Asthma
Example drug GSK2190915 Phase 2 [548641], [1572592]
Tissue Nasal and bronchial airway
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.06
Z-score: -0.05
P-value: 9.89E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 548641Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800027280)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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