Target expression details
Target General Information | |||||
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Target ID | T67416 | ||||
Target Name | Bifunctional aminoacyl-tRNA synthetase | ||||
Synonyms | Bifunctional aminoacyltRNA synthetase; Bifunctional glutamate/prolinetRNA ligase; Cell proliferationinducing gene 32 protein; GluRS; GlutamatylprolyltRNA synthetase; ProlinetRNA ligase; EPRS | ||||
Target Type | Clinical Trial | ||||
Gene Name | EPRS | ||||
Biochemical Class | Carbon-oxygen ligase | ||||
UniProt ID | SYEP_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Muscular atrophy | ||||
Example drug | HT-100 | Phase 2 | [525293], [1572592] | ||
Tissue | Muscle tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: -0.56 Z-score: -1.70 P-value: 1.16E-05 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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