Target General Information
Target ID T67416
Target Name Bifunctional aminoacyl-tRNA synthetase
Synonyms Bifunctional aminoacyltRNA synthetase; Bifunctional glutamate/prolinetRNA ligase; Cell proliferationinducing gene 32 protein; GluRS; GlutamatylprolyltRNA synthetase; ProlinetRNA ligase; EPRS
Target Type Clinical Trial
Gene Name EPRS
Biochemical Class Carbon-oxygen ligase
UniProt ID SYEP_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Muscular atrophy
Example drug HT-100 Phase 2 [525293], [1572592]
Tissue Muscle tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.56
Z-score: -1.70
P-value: 1.16E-05
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 525293ClinicalTrials.gov (NCT02525302) HT-100 Long-term Study in DMD Patients Who Completed HALO-DMD-02.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.