Target General Information
Target ID T73724
Target Name Neuronal ACh receptor beta-4
Synonyms Beta-4 nAChR; CHRNB4
Target Type Discontinued
Gene Name CHRNB4
Biochemical Class Ion transport
UniProt ID ACHB4_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Alzheimer's disease
Example drug SIB-1553A Discontinued in Phase 2 [546683], [1572592]
Tissue Entorhinal cortex
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: 9.66E-03
Z-score: 0.06
P-value: 8.30E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 546683Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800009631)
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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