Target General Information
Target ID T82841
Target Name Insulin
Synonyms Insulin; Insulin A chain; INS
Target Type Successful
Gene Name INS
Biochemical Class Insulin family
UniProt ID INS_HUMAN
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals
Disease Type 2 diabetes
Example drug Insulin-detemir Approved [536361], [551186], [1572592]
Tissue Liver tissue
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual Fold-change: -0.12
Z-score: -0.46
P-value: 6.70E-01
Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
Target Gene Expression Profiles in Other Tissues of Healthy Individuals
Reference
Ref 5511862005 approvals: Safety first. Nature Reviews Drug Discovery 5, 92-93 (February 2006).
Ref 536361Natural products as sources of new drugs over the last 25 years. J Nat Prod. 2007 Mar;70(3):461-77. Epub 2007 Feb 20.
Ref 1572592NCBI GEO: archive for functional genomics data sets--update.

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