Target expression details
Target General Information | |||||
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Target ID | T98896 | ||||
Target Name | A disintegrin and metalloproteinase with thrombospondin motifs 5 | ||||
Synonyms | ADAMTS-5; A disintegrin and metalloproteinase with thrombospondinmotifs 5; ADAM-TS 11; ADAM-TS 5; ADAM-TS5; ADMP-2; Aggrecanase-2; ADAMTS5 | ||||
Target Type | Clinical Trial | ||||
Gene Name | ADAMTS5 | ||||
Biochemical Class | Peptidase | ||||
UniProt ID | ATS5_HUMAN | ||||
Target Gene Expression Profiles in the Disease-Relevant Drug Targeted Tissue of the Patients and Healthy Individuals | |||||
Disease | Osteoarthritis | ||||
Example drug | AGG-523 | Phase 1 | [521997], [1572592] | ||
Tissue | Synovial tissue | ||||
Level of differential expression between the patients in the disease section of the tissue and the tissues of healthy individual | Fold-change: 0.24 Z-score: 0.26 P-value: 6.40E-01 |
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Target gene expression profiles of the patients in the disease section of the tissue
Target gene expression profiles in the tissue of healthy individual
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Target Gene Expression Profiles in Other Tissues of Healthy Individuals | |||||
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