Target General Infomation |
Target ID |
T28705
|
Former ID |
TTDR01413
|
Target Name |
mRNA of Caspase 8
|
Gene Name |
CASP8
|
Synonyms |
Apoptotic cysteine protease (mRNA); Apoptotic protease Mch5 (mRNA); CAP4 (mRNA); CASP8 (mRNA); Caspase8 (mRNA); Caspase8 subunit p10 (mRNA); FADDhomologous ICE/ced3like protease (mRNA); FADDlike ICE (mRNA); FLICE (mRNA); ICElike apoptotic protease 5 (mRNA); MACH (mRNA); MORT1associated ced3 homolog (mRNA); CASP8
|
Target Type |
Research
|
BioChemical Class |
Peptidase
|
Target Validation |
T28705
|
UniProt ID |
|
EC Number |
EC 3.4.22.61
|
Sequence |
MDFSRNLYDIGEQLDSEDLASLKFLSLDYIPQRKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLITYLNTRKEEMERELQTPGRAQISAYRVMLYQISEEVSRSELRSF KFLLQEEISKCKLDDDMNLLDIFIEMEKRVILGEGKLDILKRVCAQINKSLLKIINDYEE FSKERSSSLEGSPDEFSNGEELCGVMTISDSPREQDSESQTLDKVYQMKSKPRGYCLIIN NHNFAKAREKVPKLHSIRDRNGTHLDAGALTTTFEELHFEIKPHDDCTVEQIYEILKIYQ LMDHSNMDCFICCILSHGDKGIIYGTDGQEAPIYELTSQFTGLKCPSLAGKPKVFFIQAC QGDNYQKGIPVETDSEEQPYLEMDLSSPQTRYIPDEADFLLGMATVNNCVSYRNPAEGTW YIQSLCQSLRERCPRGDDILTILTEVNYEVSNKDDKKNMGKQMPQPTFTLRKKLVFPSD
|
Target Expression Profile (TEP) and Drug Resistance Mutation (DRM) |
Pathways |
References |
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