Target General Infomation
Target ID
T01447
Target Name
NEDD8-activating enzyme
Target Type
Clinical Trial
Disease Advanced malignancies [ICD9: 140-229; ICD10: C00-C96]
BioChemical Class
Ligases (EC:6)
UniProt ID
EC Number
EC 6.3.2.-
Drugs and Mode of Action
Drug(s) MLN4924 Drug Info Phase 1 Advanced malignancies [537215]
Modulator MLN4924 Drug Info
References
Ref 537215Drug discovery: Fresh target for cancer therapy. Nature. 2009 Apr 9;458(7239):709-10.

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