Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T46937 | Target Info | |||
| Target Name | P2Y purinoceptor 12 (P2RY12) | ||||
| Synonyms |
SP1999; P2Y12 platelet ADP receptor; P2Y12; P2Y(cyc); P2Y(ADP)P2Y purinoceptor 12; P2Y(ADP); P2Y(AC); P2T(AC); P2RY12; Nucleotide P2Y(12) receptor; Adenosine P2Y12 receptor; ADPG-R; ADP-glucose receptor
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| Target Type | Successful Target | ||||
| Gene Name | P2RY12 | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Cytochrome P450 2B6 (CYP2B6) | Literature-reported Target | ||||
| UniProt ID | CP2B6_HUMAN | |||||
| Gene Name | CYP2B6 | |||||
| Synonyms |
Cytochrome P450 IIB1; CYPIIB6; 1,4-cineole 2-exo-monooxygenase
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| Representative Drug(s) | Clopidogrel | Drug Info | Ki = 500 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Mechanism-based inactivation (MBI) of cytochrome P450 enzymes: structure-activity relationships and discovery strategies to mitigate drug-drug interaction risks. J Med Chem. 2012 Jun 14;55(11):4896-933. | ||||
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