Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T59845 | Target Info | |||
| Target Name | Serine/threonine PP1-alpha (PPP1CA) | ||||
| Synonyms |
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit; Protein phosphatase 1alpha; PPP1A; PP-1A
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| Target Type | Successful Target | ||||
| Gene Name | PPP1CA | ||||
| Biochemical Class | Phosphoric monoester hydrolase | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Protein phosphatase 2C beta (PPM1B) | Co-Target | ||||
| UniProt ID | PPM1B_HUMAN | |||||
| Gene Name | PPM1B | |||||
| Synonyms |
Protein phosphatase 1B; Protein phosphatase 2C isoform beta; PP2C-beta
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| Representative Drug(s) | Drug Info | IC50 = 430 nM | [1] | |||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Modified norcantharidins; synthesis, protein phosphatases 1 and 2A inhibition, and anticancer activity. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1969-73. | ||||
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