Co-Target(s) Information
Target General Information | Top | ||||
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Target ID | T92076 | Target Info | |||
Target Name | Extracellular calcium-sensing receptor (CASR) | ||||
Synonyms |
hCasR; Parathyroid cell calciumreceptor; Parathyroid cell calcium-sensing receptor 1; Parathyroid calcium receptor; Parathyroid Cell calcium-sensing receptor; PCaR1; GPRC2A; CaSR
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Target Type | Successful Target | ||||
Gene Name | CASR | ||||
Biochemical Class | GPCR glutamate | ||||
UniProt ID |
Co-Targets of This Target | Top | |||||
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Co-Target Name | Strychnine-binding glycine receptor (GLRA1) | Successful Target | ||||
UniProt ID | GLRA1_HUMAN | |||||
Gene Name | GLRA1 | |||||
Synonyms |
Strychnine-insensitive glycine receptor; Strychnine binding subunit; Glycine receptor 48 kDa subunit; GLRA1
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Representative Drug(s) | Cinacalcet | Drug Info | EC50 = 320 nM | [1] |
References | Top | ||||
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REF 1 | Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor alpha1 for the treatment of pain. J Med Chem. 2015 Apr 9;58(7):2958-66. |
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