Co-Target(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T92076 | Target Info | |||
| Target Name | Extracellular calcium-sensing receptor (CASR) | ||||
| Synonyms |
hCasR; Parathyroid cell calciumreceptor; Parathyroid cell calcium-sensing receptor 1; Parathyroid calcium receptor; Parathyroid Cell calcium-sensing receptor; PCaR1; GPRC2A; CaSR
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| Target Type | Successful Target | ||||
| Gene Name | CASR | ||||
| Biochemical Class | GPCR glutamate | ||||
| UniProt ID | |||||
| Co-Targets of This Target | Top | |||||
|---|---|---|---|---|---|---|
| Co-Target Name | Strychnine-binding glycine receptor (GLRA1) | Successful Target | ||||
| UniProt ID | GLRA1_HUMAN | |||||
| Gene Name | GLRA1 | |||||
| Synonyms |
Strychnine-insensitive glycine receptor; Strychnine binding subunit; Glycine receptor 48 kDa subunit; GLRA1
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| Representative Drug(s) | Cinacalcet | Drug Info | EC50 = 320 nM | [1] | ||
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | Ensemble-based virtual screening for cannabinoid-like potentiators of the human glycine receptor alpha1 for the treatment of pain. J Med Chem. 2015 Apr 9;58(7):2958-66. | ||||
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