Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D06XNT
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| Former ID |
DNC009940
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| Drug Name |
4-(2-Phenylacetamidomethyl)benzenesulfonamide
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| Synonyms |
2-phenyl-N-(4-sulfamoylbenzyl)acetamide; 41352-39-0; 4itp; sulfonamide deriv., 7b; 4-(2-Phenylacetamidomethyl)benzenesulfonamide; AC1N3X6Y; 2-phenyl-N-[(4-sulfamoylphenyl)methyl]acetamide; Oprea1_692071; ARONIS26431; CHEMBL574783; BDBM35734; MolPort-010-990-071; ZINC6864120; STL261373; AKOS003796845; MCULE-9432670742; 4-phenylacetamidomethyl-benzenesulfonamide; BB0294421; 4-(Phenylacetylaminomethyl)benzenesulfonamide; KS-00004825; N-[4-(aminosulfonyl)benzyl]-2-phenylacetamide; Benzeneacetamide, N-[[4-(aminosulfonyl)phenyl]methy
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H16N2O3S
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| Canonical SMILES |
C1=CC=C(C=C1)CC(=O)NCC2=CC=C(C=C2)S(=O)(=O)N
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| InChI |
1S/C15H16N2O3S/c16-21(19,20)14-8-6-13(7-9-14)11-17-15(18)10-12-4-2-1-3-5-12/h1-9H,10-11H2,(H,17,18)(H2,16,19,20)
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| InChIKey |
FTDLZZRRCJRQAA-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase I (CA-I) | Target Info | Inhibitor | [1] | |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Pathwhiz Pathway | Gastric Acid Production | |||
| Pathway Interaction Database | C-MYB transcription factor network | |||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors. Aromatic/heterocyclic sulfonamides incorporating phenacetyl, pyridylacetyl and thienylacetyl tails act as potent inh... Bioorg Med Chem. 2009 Jul 15;17(14):4894-9. | |||
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