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| Target and Pathway |
Top |
| Target(s) |
Nitric-oxide synthase brain (NOS1) |
Target Info
|
Inhibitor |
[2], [3] |
| Nitric-oxide synthase endothelial (NOS3) |
Target Info
|
Inhibitor |
[3], [4] |
| Nitric-oxide synthase inducible (NOS2) |
Target Info
|
Inhibitor |
[2], [3] |
| References |
Top |
| REF 1 |
URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 5113).
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| REF 2 |
Fluorinated indazoles as novel selective inhibitors of nitric oxide synthase (NOS): synthesis and biological evaluation. Bioorg Med Chem. 2009 Sep 1;17(17):6180-7.
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| REF 3 |
How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6.
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| REF 4 |
Inhibitory effects of a series of 7-substituted-indazoles toward nitric oxide synthases: particular potency of 1H-indazole-7-carbonitrile. Bioorg Med Chem. 2008 Jun 1;16(11):5962-73.
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