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| Target and Pathway |
Top |
| Target(s) |
Checkpoint kinase-1 (CHK1) |
Target Info
|
Inhibitor |
[2] |
| Cyclin-dependent kinase 2 (CDK2) |
Target Info
|
Inhibitor |
[1] |
| Cyclin-dependent kinase 4 (CDK4) |
Target Info
|
Inhibitor |
[1] |
| Glycogen synthase kinase-3 beta (GSK-3B) |
Target Info
|
Inhibitor |
[2] |
| PDK-1 messenger RNA (PDK-1 mRNA) |
Target Info
|
Inhibitor |
[2] |
| References |
Top |
| REF 1 |
Dissecting the determinants of cyclin-dependent kinase 2 and cyclin-dependent kinase 4 inhibitor selectivity. J Med Chem. 2006 Sep 7;49(18):5470-7.
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| REF 2 |
Triazolo[1,5-a]pyrimidines as novel CDK2 inhibitors: protein structure-guided design and SAR. Bioorg Med Chem Lett. 2006 Mar 1;16(5):1353-7.
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