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Target and Pathway |
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Target(s) |
Receptor-interacting protein 1 (RIPK1) |
Target Info
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Inhibitor |
[2] |
References |
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REF 1 |
RIP1 inhibition blocks inflammatory diseases but not tumor growth or metastases. Cell Death Differ. 2020 Jan;27(1):161-175.
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REF 2 |
Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death. Cell Death Differ. 2021 Mar;28(3):985-1000.
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