Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D01AUI
|
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| Former ID |
DNC001322
|
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| Drug Name |
SF303
|
|||
| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Canonical SMILES |
CCCCCN=C(N)NNC=C1C=NC2=C1C=C(C=C2)OC.C(=CC(=O)O)C(=O)O
|
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| PubChem Compound ID | ||||
| PubChem Substance ID |
12015123, 14806791, 16655725, 17396897, 26612835, 26680669, 26748994, 26748995, 32963935, 37101836, 43529745, 46386624, 49681580, 49831519, 50462005, 57371904, 81043815, 91011723, 92124835, 92308420, 114787862, 118843555, 124637881, 124659006, 124799787, 125268658, 126591275, 126655823, 134340523, 135692402, 144076418, 163322681, 164234023, 165232158, 172080392, 179212682, 179295972, 184021429, 196112020, 211536225, 223662763, 226414855, 227292092, 241377086, 252158215, 252401563
|
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| SuperDrug ATC ID |
A03AE02
|
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| SuperDrug CAS ID |
cas=145158710
|
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Coagulation factor Xa (F10) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathwhiz Pathway | Coagulation | |||
| Pathway Interaction Database | Beta2 integrin cell surface interactions | |||
| Reactome | Extrinsic Pathway of Fibrin Clot Formation | |||
| Intrinsic Pathway of Fibrin Clot Formation | ||||
| Common Pathway of Fibrin Clot Formation | ||||
| Gamma-carboxylation of protein precursors | ||||
| Transport of gamma-carboxylated protein precursors from the endoplasmic reticulum to the Golgi apparatus | ||||
| Removal of aminoterminal propeptides from gamma-carboxylated proteins | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Human Complement System | ||||
| PTM: gamma carboxylation, hypusine formation and arylsulfatase activation | ||||
| Blood Clotting Cascade | ||||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | The design and synthesis of noncovalent factor Xa inhibitors. Curr Top Med Chem. 2001 Jun;1(2):137-49. | |||
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