Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D03QWO
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| Former ID |
DCL000771
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| Drug Name |
Dexefaroxan
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| Synonyms |
Dexefaroxan [INN]; (+)-(r)-2-(2-ethyl-2,3-dihydro-2-benzofuranyl)-2-imidazoline; 2-[(2R)-2-ethyl-3H-1-benzofuran-2-yl]-4,5-dihydro-1H-imidazole
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| Drug Type |
Small molecular drug
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| Indication | Parkinson disease [ICD-11: 8A00.0; ICD-9: 332] | Phase 2 | [1] | |
| Schizophrenia [ICD-11: 6A20] | Discontinued in Phase 2 | [2] | ||
| Company |
Pierre Fabre
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| Structure |
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Download2D MOL |
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| Formula |
C13H16N2O
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| Canonical SMILES |
CCC1(CC2=CC=CC=C2O1)C3=NCCN3
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| InChI |
1S/C13H16N2O/c1-2-13(12-14-7-8-15-12)9-10-5-3-4-6-11(10)16-13/h3-6H,2,7-9H2,1H3,(H,14,15)/t13-/m1/s1
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| InChIKey |
RATZLMXRALDSJW-CYBMUJFWSA-N
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| CAS Number |
CAS 143249-88-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Effects of the alpha 2-adrenoreceptor antagonist dexefaroxan on neurogenesis in the olfactory bulb of the adult rat in vivo: selective protection against neuronal death. Neuroscience. 2003;117(2):281-91. | |||
| REF 2 | The pipeline and future of drug development in schizophrenia. Mol Psychiatry. 2007 Oct;12(10):904-22. | |||
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