Drug Information
Drug General Information | Top | |||
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Drug ID |
D05PDF
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Former ID |
DIB020998
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Drug Name |
sulfonamide-01
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Synonyms |
sulfonamide-01; Oprea1_687396; GTPL4313; SCHEMBL1864265; SF-01; EU-0032819; SR-01000593746; SR-01000593746-1
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL
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Formula |
C22H23N3O5S
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Canonical SMILES |
CCOC1=CC=CC=C1N(C)S(=O)(=O)C2=CC3=C(C=C2)NC=C(C3=O)C(=O)NCC=C
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InChI |
1S/C22H23N3O5S/c1-4-12-23-22(27)17-14-24-18-11-10-15(13-16(18)21(17)26)31(28,29)25(3)19-8-6-7-9-20(19)30-5-2/h4,6-11,13-14H,1,5,12H2,2-3H3,(H,23,27)(H,24,26)
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InChIKey |
IVIJZILSKWHMIO-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | cAMP-dependent chloride channel (CFTR) | Target Info | Activator | [2] |
KEGG Pathway | ABC transporters | |||
cAMP signaling pathway | ||||
AMPK signaling pathway | ||||
Gastric acid secretion | ||||
Pancreatic secretion | ||||
Bile secretion | ||||
Vibrio cholerae infection | ||||
Reactome | ABC-family proteins mediated transport | |||
WikiPathways | ABC-family proteins mediated transport |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4313). | |||
REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 707). |
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