Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08FNJ
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| Former ID |
DIB006001
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| Drug Name |
RO-14
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| Synonyms |
Very low molecular weight heparin (venous thromboembolism), Rovi
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| Indication | Phlebothrombosis [ICD-11: GB90.3; ICD-10: I80-I82] | Phase 1 | [1] | |
| Company |
Laboratorios Farmaceuticos Rovi SA
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Antithrombin-III (ATIII) | Target Info | Modulator | [2] |
| KEGG Pathway | Complement and coagulation cascades | |||
| Panther Pathway | Blood coagulation | |||
| Pathway Interaction Database | Glypican 1 network | |||
| Reactome | Intrinsic Pathway of Fibrin Clot Formation | |||
| Common Pathway of Fibrin Clot Formation | ||||
| WikiPathways | Complement and Coagulation Cascades | |||
| Formation of Fibrin Clot (Clotting Cascade) | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | ClinicalTrials.gov (NCT00629733) Clinical Trial to Evaluate the Tolerability and Pharmacokinetics of a New Ultra Low Molecular Weight Heparin (RO-14) Administered Subcutaneously Increasing Single-doses to Healthy Male Volunteers. U.S. National Institutes of Health. | |||
| REF 2 | Pharmacological effects and clinical applications of ultra low molecular weight heparins. Drug Discov Ther. 2014 Feb;8(1):1-10. | |||
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