Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09QDP
|
|||
| Former ID |
DAP001361
|
|||
| Drug Name |
Clorgyline
|
|||
| Synonyms |
Chlorgyline; Clorgilin; Clorgilina; Clorgiline; Clorgilinum; Clorgiline [INN]; M and B 9302; Clorgilina [INN-Spanish]; Clorgiline (INN); Clorgilinum [INN-Latin]; M & B 9302; N-methyl-n-propargyl-3-(2,4-dichlorophenoxy)propylamine; N-(3-(2,4-Dichlorophenoxy)propyl)-N-methyl-2-propynylamine; N-[3-(2,4-DICHLOROPHENOXY)PROPYL]-N-METHYL-N-PROP-2-YNYLAMINE; 2-Propyn-1-amine, N-(3-(2,4-dichlorophenoxy)propyl)-N-methyl-(9CI); 3-(2,4-dichlorophenoxy)-N-methyl-N-prop-2-ynylpropan-1-amine
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Parkinson disease [ICD-11: 8A00.0] | Approved | [1], [2], [3] | |
| Skin imperfections [ICD-11: EK71; ICD-10: L91.8] | Patented | [4] | ||
| Therapeutic Class |
Antiparkinson Agents
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C13H15Cl2NO
|
|||
| Canonical SMILES |
CN(CCCOC1=C(C=C(C=C1)Cl)Cl)CC#C
|
|||
| InChI |
1S/C13H15Cl2NO/c1-3-7-16(2)8-4-9-17-13-6-5-11(14)10-12(13)15/h1,5-6,10H,4,7-9H2,2H3
|
|||
| InChIKey |
BTFHLQRNAMSNLC-UHFFFAOYSA-N
|
|||
| CAS Number |
CAS 17780-72-2
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID |
13850, 3249453, 5551145, 7888938, 8152714, 11111452, 11111453, 11466372, 11467492, 11486064, 15197430, 17397401, 29223477, 46507410, 46515873, 47216895, 47736618, 47959893, 48259379, 48334629, 49698444, 50026762, 50111129, 53787182, 57322251, 57389000, 74906189, 85209991, 85787507, 89449655, 90341614, 103167716, 104306235, 121598837, 124749963, 124880698, 126407870, 127564762, 134338573, 134993341, 137237445, 137725548, 160967085, 163425653, 163667991, 178103249, 179148711, 196408559, 198975950, 226443490
|
|||
| ChEBI ID |
CHEBI:3763
|
|||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6636). | |||
| REF 2 | Further investigation into the mechanism of tachykinin NK(2) receptor-triggered serotonin release from guinea-pig proximal colon. J Pharmacol Sci. 2009 May;110(1):122-6. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 4 | Novel monoamine oxidase inhibitors: a patent review (2012 - 2014).Expert Opin Ther Pat. 2015 Jan;25(1):91-110. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.