Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0F4EL
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| Former ID |
DNC009182
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| Drug Name |
LEUCETTAMINE A
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| Synonyms |
Leucettamol A; Leucettamine A (lipid); 151124-32-2; AC1O5ZHI; 5,8,11,14,17,20-Triacontahexaene-3,28-diol, 2,29-diamino-, (2R*,3S*,5Z,8Z,11Z,14Z,20Z,28S*,29R*)-(+-)-; 334010-39-8; 5,8,11,14,17,20-Triacontahexaene-3,28-diol, 2,29-diamino-, (2R*,3S*,5Z,8Z,11Z,14Z,20Z,28S*,29R*)-; 5,8,11,14,17,20-Triacontahexaene-3,28-diol, 2,29-diamino-, (2R,3S,5Z,8Z,11Z,14Z,20Z,28S,29R)-rel-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C20H19N3O4
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| Canonical SMILES |
CN1C(=C(N=C1N)CC2=CC3=C(C=C2)OCO3)CC4=CC5=C(C=C4)OCO5
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| InChI |
1S/C20H19N3O4/c1-23-15(7-13-3-5-17-19(9-13)27-11-25-17)14(22-20(23)21)6-12-2-4-16-18(8-12)26-10-24-16/h2-5,8-9H,6-7,10-11H2,1H3,(H2,21,22)
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| InChIKey |
CHUHMZZQHYOKBF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukotriene B4 receptor 1 (LTB4R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| NetPath Pathway | IL4 Signaling Pathway | |||
| Reactome | Leukotriene receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Nucleotide GPCRs | |||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| Spinal Cord Injury | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | New leukotriene B4 receptor antagonist: leucettamine A and related imidazole alkaloids from the marine sponge Leucetta microraphis. J Nat Prod. 1993 Jan;56(1):116-21. | |||
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