Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0G6UQ
|
|||
| Former ID |
DIB008183
|
|||
| Drug Name |
EP-42675
|
|||
| Synonyms |
NAPAP analogs, Organon; Factor IIa/Factor X dual inhibitors (thrombosis), Endotis; Factor IIa/Factor X dual inhibitors (thrombosis), Organon; NAPAP-PS conjugate (thrombosis), Endotis; NAPAP-PS conjugate (thrombosis), Organon
Click to Show/Hide
|
|||
| Indication | Thrombosis [ICD-11: DB61-GB90; ICD-10: I80-I82] | Phase 1 | [1] | |
| Company |
Organon BioSciences
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C79H125N7Na8O56S7
|
|||
| Canonical SMILES |
CC1=CC(=C(C(=C1S(=O)(=O)NC(CC(=O)NCCCC(=O)NCCOCCOCCOCCOC2C(OC(C(C2OC)OC)OC3C(C(C(OC3C(=O)O)OC4C(OC(C(C4OS(=O)(=O)O)OS(=O)(=O)O)OC5C(C(C(OC5C(=O)O)OC6C(OC(C(C6OC)OS(=O)(=O)O)OC)COS(=O)(=O)O)OC)OC)COS(=O)(=O)O)OC)OC)COS(=O)(=O)O)C(=O)NC(CC7=CC=C(C=C7)C(=N)N)C(=O)N8CCCCC8)C)C)OC.[Na].[Na].[Na].[Na].[Na].[Na].[Na].[Na]
|
|||
| InChI |
1S/C79H125N7O56S7.8Na/c1-39-33-46(115-4)40(2)41(3)69(39)143(95,96)85-44(71(89)84-45(72(90)86-24-14-13-15-25-86)34-42-18-20-43(21-19-42)70(80)81)35-51(88)82-22-16-17-50(87)83-23-26-124-27-28-125-29-30-126-31-32-127-52-47(36-128-144(97,98)99)132-76(64(120-9)55(52)116-5)136-59-57(118-7)66(122-11)78(139-62(59)73(91)92)135-54-49(38-130-146(103,104)105)133-79(68(142-149(112,113)114)61(54)140-147(106,107)108)137-60-58(119-8)65(121-10)77(138-63(60)74(93)94)134-53-48(37-129-145(100,101)102)131-75(123-12)67(56(53)117-6)141-148(109,110)111;;;;;;;;/h18-21,33,44-45,47-49,52-68,75-79,85H,13-17,22-32,34-38H2,1-12H3,(H3,80,81)(H,82,88)(H,83,87)(H,84,89)(H,91,92)(H,93,94)(H,97,98,99)(H,100,101,102)(H,103,104,105)(H,106,107,108)(H,109,110,111)(H,112,113,114);;;;;;;;/t44-,45+,47+,48+,49+,52+,53+,54+,55-,56-,57-,58-,59-,60-,61-,62-,63+,64+,65+,66+,67+,68+,75-,76+,77+,78+,79+;;;;;;;;/m0......../s1
|
|||
| InChIKey |
QYMUZBCRFQFXJQ-KIDSDGJESA-N
|
|||
| CAS Number |
CAS 343776-67-0
|
|||
| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800023539) | |||
| REF 2 | EP42675, a synthetic parenteral dual-action anticoagulant: pharmacokinetics, pharmacodynamics, and absence of interactions with antiplatelet drugs. J Thromb Haemost. 2014 Jan;12(1):24-33. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.