Drug Information
Drug General Information | Top | |||
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Drug ID |
D0KS3G
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Drug Name |
PMID29166791-Compound-AMPCP
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Drug Type |
Small molecular drug
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Company |
ARCUS BIOSCIENCES, INCVITAE PHARMACEUTICALS, INC
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Ecto-5'-nucleotidase (CD73) | Target Info | Inhibitor | [1] |
Target's Patent Info | Ecto-5'-nucleotidase (CD73) | Target's Patent Info | [1] | |
BioCyc | Purine nucleotides degradation | |||
Urate biosynthesis/inosine 5'-phosphate degradation | ||||
Adenosine nucleotides degradation | ||||
KEGG Pathway | Purine metabolism | |||
Pyrimidine metabolism | ||||
Nicotinate and nicotinamide metabolism | ||||
Metabolic pathways | ||||
Panther Pathway | Purine metabolism | |||
Pyrimidine Metabolism | ||||
Pathway Interaction Database | HIF-1-alpha transcription factor network | |||
Reactome | Purine catabolism | |||
WikiPathways | Differentiation Pathway | |||
miR-targeted genes in muscle cell - TarBase | ||||
miR-targeted genes in lymphocytes - TarBase | ||||
miR-targeted genes in epithelium - TarBase | ||||
Metabolism of nucleotides |
References | Top | |||
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REF 1 | Evaluation of WO2017098421: GSK's benzothiazine compounds as CD73 inhibitor filings.Expert Opin Ther Pat. 2018 Feb;28(2):167-171. |
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