Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0M9QJ
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| Former ID |
DIB020715
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| Drug Name |
PHT-427
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| Synonyms |
PHT 427; PHT427
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C20H31N3O2S2
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| Canonical SMILES |
CCCCCCCCCCCCC1=CC=C(C=C1)S(=O)(=O)NC2=NN=CS2
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| InChI |
1S/C20H31N3O2S2/c1-2-3-4-5-6-7-8-9-10-11-12-18-13-15-19(16-14-18)27(24,25)23-20-22-21-17-26-20/h13-17H,2-12H2,1H3,(H,22,23)
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| InChIKey |
BYWWNRBKPCPJMG-UHFFFAOYSA-N
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| CAS Number |
CAS 1191951-57-1
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| PubChem Compound ID | ||||
| PubChem Substance ID |
85260779, 97080358, 99381500, 103719331, 104158730, 104253210, 124757336, 125164140, 136340169, 136348251, 136367546, 136946510, 138536515, 152258383, 160647220, 162011692, 162037665, 163685772, 174006508, 174526500, 180386847, 185973855, 223382614, 223705082, 224506936, 225331053, 226627378, 241377076, 242586968, 248989086, 249565689, 252158201, 252160525, 252220182, 252473073
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| References | Top | |||
|---|---|---|---|---|
| REF 1 | Computational modeling of novel inhibitors targeting the Akt pleckstrin homology domain. Bioorg Med Chem. 2009 Oct 1;17(19):6983-92. | |||
| REF 2 | Molecular pharmacology and antitumor activity of PHT-427, a novel Akt/phosphatidylinositide-dependent protein kinase 1 pleckstrin homology domain inhibitor. Mol Cancer Ther. 2010 Mar;9(3):706-17. | |||
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