Drug Information
Drug General Information | Top | |||
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Drug ID |
D0N9ZR
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Former ID |
DNC007189
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Drug Name |
6-bromo-5-methyl-1H-indole-2,3-dione
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Synonyms |
6-bromo-5-methyl-1H-indole-2,3-dione; 6-BROMO-5-METHYLISATIN; 306325-13-3; 6-bromo-5-methylindoline-2,3-dione; 6-bromo-5-methyl-2,3-dihydro-1H-indole-2,3-dione; 6-bromo-5-methyl-1H-benzo[d]azolidine-2,3-dione; AC1LW5IO; CBMicro_014209; Isatin-based compound, 58; SCHEMBL5526009; AC1Q2O90; CHEMBL221830; ARONIS016716; CTK7H5981; BDBM22838; BBC/891; MolPort-001-022-207; DQZFCBOXZKQQPM-UHFFFAOYSA-N; ALBB-012856; ZX-AN011645; ZINC2052963; SMSF0004612; STK042825; SBB071631; AKOS000484014; MCULE-6005372434; FCH1317267; CB09212; KS-000049B7
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C9H6BrNO2
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Canonical SMILES |
CC1=CC2=C(C=C1Br)NC(=O)C2=O
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InChI |
1S/C9H6BrNO2/c1-4-2-5-7(3-6(4)10)11-9(13)8(5)12/h2-3H,1H3,(H,11,12,13)
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InChIKey |
DQZFCBOXZKQQPM-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Liver carboxylesterase (CES1) | Target Info | Inhibitor | [1] |
KEGG Pathway | Drug metabolism - other enzymes | |||
Metabolic pathways | ||||
Pathway Interaction Database | E2F transcription factor network | |||
WikiPathways | NRF2 pathway | |||
Nuclear Receptors Meta-Pathway | ||||
Heroin metabolism | ||||
Irinotecan Pathway | ||||
Fluoropyrimidine Activity | ||||
Phase I biotransformations, non P450 |
References | Top | |||
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REF 1 | Selective inhibition of carboxylesterases by isatins, indole-2,3-diones. J Med Chem. 2007 Apr 19;50(8):1876-85. |
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