miRNA Details
miRNA General Information | |||||
---|---|---|---|---|---|
miRNA Mature ID | hsa-miR-371a-3p | ||||
miRNA Stemloop AC | MI0000779 | ||||
miRNA Stemloop ID | hsa-mir-371a | ||||
Sequence | aagugccgccaucuuuugagugu | ||||
TTD Target(s) Regulated by This miRNA | Dickkopf-related protein 1 (DKK1) | Clinical trial Target | Target Info | [1] | |
Proto-oncogene c-Myc (MYC) | Literature-reported Target | Target Info | [2] | ||
Protein(s) Regulated by This miRNA | 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 | Regulated Protein | [3] | ||
Peroxiredoxin-6 | Regulated Protein | [3] | |||
Syntaxin-12 | Regulated Protein | [3] | |||
References | |||||
REF 1 | -Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/-catenin-signaling pathway. Oncogene. 2012 Jun 14;31(24):2968-78. | ||||
REF 2 | Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20471-6. | ||||
REF 3 | Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.Nat Commun. 2016 Aug 3;7:12351. |
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