miRNA General Information
miRNA Mature ID hsa-miR-371a-3p
miRNA Stemloop AC MI0000779
miRNA Stemloop ID hsa-mir-371a
Sequence aagugccgccaucuuuugagugu
TTD Target(s) Regulated by This miRNA Dickkopf-related protein 1 (DKK1) Clinical trial Target Target Info [1]
Proto-oncogene c-Myc (MYC) Literature-reported Target Target Info [2]
Protein(s) Regulated by This miRNA 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-4 Regulated Protein [3]
Peroxiredoxin-6 Regulated Protein [3]
Syntaxin-12 Regulated Protein [3]
References
REF 1 -Catenin/LEF1 transactivates the microRNA-371-373 cluster that modulates the Wnt/-catenin-signaling pathway. Oncogene. 2012 Jun 14;31(24):2968-78.
REF 2 Stem cell-like micro-RNA signature driven by Myc in aggressive liver cancer. Proc Natl Acad Sci U S A. 2010 Nov 23;107(47):20471-6.
REF 3 Functional screening implicates miR-371-3p and peroxiredoxin 6 in reversible tolerance to cancer drugs.Nat Commun. 2016 Aug 3;7:12351.

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