miRNA General Information
miRNA Mature ID hsa-miR-377-3p
miRNA Stemloop AC MI0000785
miRNA Stemloop ID hsa-mir-377
Sequence aucacacaaaggcaacuuuugu
TTD Target(s) Regulated by This miRNA Cellular tumor antigen p53 (TP53) Clinical trial Target Target Info [1]
DNA [cytosine-5]-methyltransferase 1 (DNMT1) Clinical trial Target Target Info [2]
Superoxide dismutase Cu-Zn (SOD Cu-Zn) Clinical trial Target Target Info [3]
Superoxide dismutase Mn (SOD Mn) Clinical trial Target Target Info [3]
Hematopoietic progenitor cell antigen CD34 (CD34) Clinical trial Target Target Info [4]
Phosphatase and tensin homolog (PTEN) Literature-reported Target Target Info [5]
PAK-1 protein kinase (PAK1) Literature-reported Target Target Info [3]
Protein(s) Regulated by This miRNA Metalloproteinase inhibitor 1 Regulated Protein [1]
Protein phosphatase 1A Regulated Protein [3]
References
REF 1 MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes. Oncol Rep. 2015 Jul;34(1):203-10.
REF 2 miR-377 induces senescence in human skin fibroblasts by targeting DNA methyltransferase 1. Cell Death Dis. 2017 Mar 9;8(3):e2663.
REF 3 MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J. 2008 Dec;22(12):4126-35.
REF 4 Identification of apoptosis-related microRNAs and their target genes in myocardial infarction post-transplantation with skeletal myoblasts. J Transl Med. 2015 Aug 19;13:270.
REF 5 Remodeling of Ago2-mRNA interactions upon cellular stress reflects miRNA complementarity and correlates with altered translation rates. Genes Dev. 2013 Jul 15;27(14):1624-32.
REF 6 MicroRNA-377 predicts poor clinical outcome of gastric cancer and induces tumorigenesis by targeting multiple tumor-suppressor genes. Oncol Rep. 2015 Jul;34(1):203-10.
REF 7 MicroRNA-377 is up-regulated and can lead to increased fibronectin production in diabetic nephropathy. FASEB J. 2008 Dec;22(12):4126-35.

If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.