miRNA General Information
miRNA Mature ID hsa-miR-561-3p
miRNA Stemloop AC MI0003567
miRNA Stemloop ID hsa-mir-561
Sequence caaaguuuaagauccuugaagu
TTD Target(s) Regulated by This miRNA Proto-oncogene c-Myc (MYC) Literature-reported Target Target Info [1]
Orphan nuclear receptor DAX-1 (NR0B1) Literature-reported Target Target Info [2]
References
REF 1 MicroRNA-561 inhibits gastric cancercell proliferation and invasion by downregulating c-Myc expression. Am J Transl Res. 2016 Sep 15;8(9):3802-3811.
REF 2 MicroRNA-561 promotes acetaminophen-induced hepatotoxicity in HepG2 cells and primary human hepatocytes through downregulation of the nuclear receptor corepressor dosage-sensitive sex-reversal adrenal hypoplasia congenital critical region on the X chromosome, gene 1 (DAX-1). Drug Metab Dispos. 2014 Jan;42(1):44-61.

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