Content Navigation
( All
None )
| Protein General Information |
Top |
| Full Name |
Cyclin-A1 (CCNA1)
|
| UniProt ID |
CCNA1_HUMAN
|
| Gene Name |
CCNA1
|
| Gene ID |
8900
|
| Interacting TTD Target Information |
Top |
| Interacting Clinical trial Target(s) |
Cyclin-dependent kinase 2 (CDK2) |
Target Info
|
PPI Info
|
[1] |
| Interacting Literature-reported Target(s) |
Melanoma differentiation-associated protein 6 (CDKN1A) |
Target Info
|
PPI Info
|
[2] |
| S-phase kinase-associated protein 2 (SKP2) |
Target Info
|
PPI Info
|
[3] |
| References |
Top |
| REF 1 |
Degradation of cyclin A does not require its phosphorylation by CDC2 and cyclin-dependent kinase 2. J Biol Chem. 2000 Feb 4;275(5):3158-67.
|
| REF 2 |
Highly potent p21(WAF1)-derived peptide inhibitors of CDK-mediated pRb phosphorylation: delineation and structural insight into their interactions with cyclin A. J Pept Res. 2002 Nov;60(5):257-70.
|
| REF 3 |
Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction. Nat Cell Biol. 2009 Apr;11(4):397-408.
|
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.
