Protein-Protein Interaction Details
Protein General Information (TTD Target) | Top | ||||
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Full Name | Tyrosine-protein kinase EIF2AK2 (p68) | Patented-recorded | Target Info | ||
UniProt ID | E2AK2_HUMAN | ||||
Gene Name | EIF2AK2 | ||||
Gene ID | 5610 |
Interacting TTD Target Information | Top | ||||
---|---|---|---|---|---|
Interacting Successful Target(s) | Heat shock protein 90 alpha (HSP90A) | Target Info | PPI Info | [1] | |
Interacting Clinical trial Target(s) | Cellular tumor antigen p53 (TP53) | Target Info | PPI Info | [2] | |
Nucleophosmin (NPM1) | Target Info | PPI Info | [3] | ||
Interacting Patented-recorded Target(s) | Signal transducer and activator of transcription 1 (STAT1) | Target Info | PPI Info | [4] | |
Tyrosine-protein kinase EIF2AK2 (p68) | Target Info | PPI Info | [5] |
References | Top | ||||
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REF 1 | Quantitative analysis of HSP90-client interactions reveals principles of substrate recognition. Cell. 2012 Aug 31;150(5):987-1001. | ||||
REF 2 | The double-stranded RNA activated protein kinase PKR physically associates with the tumor suppressor p53 protein and phosphorylates human p53 on serine 392 in vitro. Oncogene. 1999 Apr 29;18(17):2690-702. | ||||
REF 3 | Antiviral action of the tumor suppressor ARF. EMBO J. 2006 Sep 20;25(18):4284-92. | ||||
REF 4 | Physical association between STAT1 and the interferon-inducible protein kinase PKR and implications for interferon and double-stranded RNA signaling pathways. EMBO J. 1997 Mar 17;16(6):1291-304. | ||||
REF 5 | PKR stimulates NF-kappaB irrespective of its kinase function by interacting with the IkappaB kinase complex. Mol Cell Biol. 2000 Jul;20(13):4532-42. |
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