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| Protein General Information (TTD Target) |
Top |
| Full Name |
HIF-prolyl hydroxylase 2 (HPH-2)
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Patented-recorded
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Target Info
|
| UniProt ID |
EGLN1_HUMAN
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| Gene Name |
EGLN1
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| Gene ID |
54583
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| References |
Top |
| REF 1 |
Defective Tibetan PHD2 binding to p23 links high altitude adaption to altered oxygen sensing. J Biol Chem. 2014 May 23;289(21):14656-65.
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| REF 2 |
Myeloid translocation gene-16 co-repressor promotes degradation of hypoxia-inducible factor 1. PLoS One. 2015 May 14;10(5):e0123725.
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| REF 3 |
Identification of the hypoxia-inducible factor 2 nuclear interactome in melanoma cells reveals master proteins involved in melanoma development. Mol Cell Proteomics. 2013 Mar;12(3):736-48.
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| REF 4 |
The LIMD1 protein bridges an association between the prolyl hydroxylases and VHL to repress HIF-1 activity. Nat Cell Biol. 2012 Jan 29;14(2):201-8.
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