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Protein General Information (TTD Target) |
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Full Name |
Proto-oncogene c-Met (MET)
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Successful
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Target Info
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UniProt ID |
MET_HUMAN
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Gene Name |
MET
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Gene ID |
4233
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
Hepatocyte growth factor (HGF) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
Signal transduction protein CBL (CBL) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Scatter factor and hepatocyte growth factor are indistinguishable ligands for the MET receptor. EMBO J. 1991 Oct;10(10):2867-78.
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REF 2 |
Somatic mutations lead to an oncogenic deletion of met in lung cancer. Cancer Res. 2006 Jan 1;66(1):283-9.
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