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| Protein General Information |
Top |
| Full Name |
E3 SUMO-protein ligase PIAS1 (PIAS1)
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| UniProt ID |
PIAS1_HUMAN
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| Gene Name |
PIAS1
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| Gene ID |
8554
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| Interacting TTD Target Information |
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| Interacting Clinical trial Target(s) |
Cellular tumor antigen p53 (TP53) |
Target Info
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PPI Info
|
[1] |
| Interacting Patented-recorded Target(s) |
Signal transducer and activator of transcription 1 (STAT1) |
Target Info
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PPI Info
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[2] |
| References |
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| REF 1 |
Involvement of PIAS1 in the sumoylation of tumor suppressor p53. Mol Cell. 2001 Sep;8(3):713-8.
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| REF 2 |
TGF-beta suppresses IFN-gamma-STAT1-dependent gene transcription by enhancing STAT1-PIAS1 interactions in epithelia but not monocytes/macrophages. J Immunol. 2007 Apr 1;178(7):4284-95.
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