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Protein General Information |
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Full Name |
Replication protein A 32 kDa subunit (RPA2)
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UniProt ID |
RFA2_HUMAN
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Gene Name |
RPA2
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Gene ID |
6118
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Interacting TTD Target Information |
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Interacting Clinical trial Target(s) |
DNA-dependent protein kinase catalytic (PRKDC) |
Target Info
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PPI Info
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[1] |
Interacting Literature-reported Target(s) |
DNA repair protein complementing XP-A cells (XPA) |
Target Info
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PPI Info
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[2] |
References |
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REF 1 |
Replication-mediated DNA damage by camptothecin induces phosphorylation of RPA by DNA-dependent protein kinase and dissociates RPA:DNA-PK complexes. EMBO J. 1999 Mar 1;18(5):1397-406.
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REF 2 |
SIRT1 regulates UV-induced DNA repair through deacetylating XPA. Mol Cell. 2010 Jul 30;39(2):247-58.
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