Protein-Protein Interaction Details
| Protein General Information | Top | ||||
|---|---|---|---|---|---|
| Full Name | Signal transducer and activator of transcription 2 (STAT2) | ||||
| UniProt ID | STAT2_HUMAN | ||||
| Gene Name | STAT2 | ||||
| Gene ID | 6773 | ||||
| Interacting TTD Target Information | Top | ||||
|---|---|---|---|---|---|
| Interacting Successful Target(s) | Epidermal growth factor receptor (EGFR) | Target Info | PPI Info | [1] | |
| Interferon alpha/beta receptor 2 (IFNAR2) | Target Info | PPI Info | [2] | ||
| Interacting Clinical trial Target(s) | CREB-binding protein (CREBBP) | Target Info | PPI Info | [3] | |
| Interferon alpha/beta receptor 1 (IFNAR1) | Target Info | PPI Info | [4] | ||
| Interacting Patented-recorded Target(s) | Signal transducer and activator of transcription 1 (STAT1) | Target Info | PPI Info | [5] | |
| References | Top | ||||
|---|---|---|---|---|---|
| REF 1 | The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells. Nat Methods. 2014 May;11(5):585-92. | ||||
| REF 2 | Stat2 binding to the interferon-alpha receptor 2 subunit is not required for interferon-alpha signaling. J Biol Chem. 2002 Mar 22;277(12):9713-21. | ||||
| REF 3 | Cooperation of Stat2 and p300/CBP in signalling induced by interferon-alpha. Nature. 1996 Sep 26;383(6598):344-7. | ||||
| REF 4 | Interaction of the transcriptional activator Stat-2 with the type I interferon receptor. J Biol Chem. 1995 Oct 20;270(42):24627-30. | ||||
| REF 5 | Urokinase induces activation and formation of Stat4 and Stat1-Stat2 complexes in human vascular smooth muscle cells. J Biol Chem. 1999 Aug 20;274(34):24059-65. | ||||
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