Target Poor or Non Binder(s) Information
| Target General Information | Top | ||||
|---|---|---|---|---|---|
| Target ID | T36483 | Target Info | |||
| Target Name | Proteinase activated receptor 1 (F2R) | ||||
| Synonyms |
Thrombin receptor; Proteinase-activated receptor 1; Protease-activated receptor-1; Protease activated receptor 1; PAR1; PAR-1; Coagulation factor II receptor; CF2R
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| Target Type | Successful Target | ||||
| Gene Name | F2R | ||||
| Biochemical Class | GPCR rhodopsin | ||||
| UniProt ID | |||||
| Poor Binders of This Target (in total, 63 binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
3-{[1-(3-Piperidin-4-yl-propionyl)-piperidine-3-carbonyl]-amino}-cyclohexanecarboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL309536; BDBM50287975
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| Activity |
IC50 ~ 50000 nM
|
[1] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-(Benzylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-2-[(1S)-1-(2,3-diaminopropanoylamino)-2-(4-fluorophenyl)ethyl]-5-methyl-1,3-oxazole-4-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL42224; BDBM50070671
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| Activity |
IC50 = 53000 nM
|
[2] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl(1H-indol-3-yl)amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143258
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| Activity |
IC50 = 54000 nM
|
[3] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-3-[[(E)-3-(4-chlorophenyl)prop-2-enoyl]amino]-1H-1,2,4-triazole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL33435; BDBM50077723
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| Activity |
EC50 = 55000 nM
|
[4] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2R)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143287
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| Activity |
IC50 ~ 55000 nM
|
[3] | |||
| Compound Name |
(1S,2S,4As,5R,6R,8aR)-1-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-5-(hydroxymethyl)-2,5,8a-trimethyl-3,4,4a,6,7,8-hexahydro-1H-naphthalene-2,6-diol
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4088070; BDBM50258032
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| Activity |
IC50 = 55000 nM
|
[5] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-1H-indole-2-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL33487; BDBM50077757
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| Activity |
IC50 = 56000 nM
|
[4] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-(Benzylamino)-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-5-methyl-2-[(1S)-1-[[2-(methylamino)acetyl]amino]-2-phenylethyl]-1,3-oxazole-4-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL296147; BDBM50070678
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| Activity |
IC50 = 60000 nM
|
[2] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-aminophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143259
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|
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| Activity |
EC50 = 60000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143265
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|
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| Activity |
IC50 = 64000 nM
|
[3] | |||
| Compound Name |
4-Oxo-1-[1-(3-piperidin-4-yl-propionyl)-piperidine-3-carbonyl]-piperidine-3-carboxylic acid
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL311554; BDBM50287970
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|
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| Activity |
IC50 = 65000 nM
|
[1] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-(4-phenylphenyl)prop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143324
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|
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| Activity |
IC50 = 66700 nM
|
[3] | |||
| Compound Name |
(2S)-5-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]carbamoylamino]-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-4-methylpentanoyl]amino]pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143312
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|
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| Activity |
EC50 = 67000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-(N-Acetyl-4-fluoroanilino)-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143306
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| Activity |
IC50 = 68000 nM
|
[3] | |||
| Compound Name |
L-Alaninamide, L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL130058; CTK0B5076; BDBM50031403
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| Activity |
EC50 = 70000 nM
|
[6] | |||
| Compound Name |
(S)-2-[(S)-2-((S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-4-methyl-pentanoylamino)-5-guanidino-pentanoylamino]-succinamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL33473; SFLLRN-NH2; TRAP6; Ser-Phe-Leu-Leu-Arg-Asn-NH2; BDBM85085; Ser-Phe-Leu-Leu-Arg-Asn-NH(2); BDBM50031392; ZINC29221575; Ser-Phe-Leu-Leu-Arg-Asn-amide trifluoroacetate salt; L-Aspartamide,L-seryl-L-phenylalanyl-L-leucyl-L-leucyl-L-arginyl-
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| Activity |
IC50 = 73000 nM
|
[2] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl(thiophen-3-yl)amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143304
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| Activity |
IC50 = 74000 nM
|
[3] | |||
| Compound Name |
Chembl4227184
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Investigative | Compound Info | ||
| Synonyms |
BDBM50461683
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|
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| Activity |
IC50 = 81000 nM
|
[7] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl(cyclopentyl)amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143262
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|
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| Activity |
IC50 = 85000 nM
|
[3] | |||
| Compound Name |
[(2R,4As,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,1,4a,6-tetramethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] methanesulfonate
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074902; BDBM50257971
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|
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| Activity |
IC50 = 87000 nM
|
[5] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-3-(4-Benzoylphenyl)-2-[[(2S)-3-[4-(diaminomethylideneamino)phenyl]-2-[[(2S)-3-(4-fluorophenyl)-2-[[(E)-3-phenylprop-2-enoyl]amino]propanoyl]amino]propanoyl]amino]propanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]amino]-5-[(4-nitro-2,1,3-benzoxadiazol-7-yl)amino]pentanoic acid
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL411798
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| Activity |
IC50 ~ 90000 nM
|
[8] | |||
| Compound Name |
(2R)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-6-[bis(dimethylamino)methylideneamino]hexanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143283
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|
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| Activity |
IC50 = 90000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-(N-Acetylanilino)-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143294
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| Activity |
IC50 = 94000 nM
|
[3] | |||
| Compound Name |
Chembl4226195
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Investigative | Compound Info | ||
| Synonyms |
BDBM50461682
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| Activity |
IC50 = 94000 nM
|
[7] | |||
| Compound Name |
N-[(2R)-1-[[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-2-[(1S)-2-(4-fluorophenyl)-1-[[2-(methylamino)acetyl]amino]ethyl]-1,3-thiazole-4-carboxamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL295849; BDBM50070664
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| Activity |
IC50 = 94000 nM
|
[2] | |||
| Compound Name |
2-[(E)-2-[(4Ar,6aR,7S,8S,10aS,10bR)-3,3,6a,10b-tetramethylspiro[1,4a,5,6,7,9,10,10a-octahydronaphtho[2,1-d][1,3]dioxine-8,2'-oxirane]-7-yl]ethenyl]-5-(3-fluorophenyl)pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4077889; BDBM50258023
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6S,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] acetate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4063603; BDBM50257982
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(1S,2R,4Ar,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)-1-oxidopyridin-1-ium-2-yl]ethenyl]-2-hydroxy-1,4a-dimethylspiro[3,4,5,7,8,8a-hexahydro-2H-naphthalene-6,2'-oxirane]-1-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4073470; BDBM50258035
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(2R,4As,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,1,4a,6-tetramethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] acetate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093859; BDBM50258058
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6S,7S,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] methanesulfonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4066363; BDBM50258028
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-[(E)-2-[(1S,2S,4Ar,8aS)-2,5,5,8a-tetramethyl-1,2,3,4,4a,8-hexahydronaphthalen-1-yl]ethenyl]-5-(3-fluorophenyl)pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4078212; BDBM50258059
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6S,7S,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] butanoate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4080194; BDBM50257998
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6S,7S,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] acetate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074969; BDBM50257981
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-[(E)-2-[(4Ar,6aR,7S,8S,10aS,10bR)-3,3,6a,10b-tetramethylspiro[1,4a,5,6,7,9,10,10a-octahydronaphtho[2,1-d][1,3]dioxine-8,2'-oxirane]-7-yl]ethenyl]-5-[3-(trifluoromethyl)phenyl]pyridine
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4074508; BDBM50258024
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-1-[2-[(1S)-2-(4-fluorophenyl)-1-[[2-(methylamino)acetyl]amino]ethyl]-1,3-thiazole-4-carbonyl]piperidine-3-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL44239; BDBM50070655
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| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
(1R,2R,4Ar,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)-1-oxidopyridin-1-ium-2-yl]ethenyl]-2-hydroxy-1,4a-dimethylspiro[3,4,5,7,8,8a-hexahydro-2H-naphthalene-6,2'-oxirane]-1-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092571; BDBM50258022
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(2R,4As,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,1,4a,6-tetramethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] ethyl carbonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104026; BDBM50257974
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(1S,2R,4As,5R,6S,8aS)-6-(1,3-dithiolan-2-yl)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-2-hydroxy-1,4a-dimethyl-2,3,4,5,6,7,8,8a-octahydronaphthalene-1-carbaldehyde
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4064870; BDBM50257940
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6R,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] methanesulfonate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4101654; BDBM50257980
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-3-cyclohexyl-1-oxopropan-2-yl]-3-[[(E)-3-(1H-indol-3-yl)prop-2-enoyl]amino]-1H-1,2,4-triazole-5-carboxamide
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL430734; BDBM50077770
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| Activity |
IC50 = 100000 nM
|
[4] | |||
| Compound Name |
Methyl (1S,2R,4aR,5S,6S,8aS)-2-butanoyloxy-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,4a-dimethylspiro[3,4,5,7,8,8a-hexahydro-2H-naphthalene-6,2'-oxirane]-1-carboxylate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4070740; BDBM50258012
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(3As,5aS,6R,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-7-hydroxy-6,9a-dimethyl-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[g][2]benzofuran-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104074; BDBM50257978
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|
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6R,7S,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] carbamate
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4096709; BDBM50257997
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(3As,5aS,6R,7S,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-7-hydroxy-6,9a-dimethyl-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[g][2]benzofuran-1-one
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Investigative | Compound Info | ||
| Synonyms |
CHEMBL4093927; BDBM50257979
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| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
2-[(1S)-1-[[(2S,3R)-2-Amino-3-methylpentanoyl]amino]-2-(4-fluorophenyl)ethyl]-N-[2-[[(2S)-1-[[(2S)-1-amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-2-oxoethyl]-N-benzyl-1,3-thiazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL1790239; BDBM50366501
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
(3As,5aS,6S,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-7-hydroxy-6,9a-dimethyl-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[g][2]benzofuran-1-one
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4086167; BDBM50257977
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
[(3As,5aS,6R,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] acetate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4085223; BDBM50258029
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-[(2S)-6-Amino-1-[[(2S)-5-(diaminomethylideneamino)-1-oxo-1-(2-phenylethylamino)pentan-2-yl]amino]-1-oxohexan-2-yl]-2-[(1S)-2-(4-fluorophenyl)-1-[[2-(methylamino)acetyl]amino]ethyl]-1,3-thiazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL44763; BDBM50070659
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
[(3As,5aS,6R,7R,9aR,9bR)-6-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-6,9a-dimethyl-1-oxo-3a,4,5,5a,7,8,9,9b-octahydro-3H-benzo[e][2]benzofuran-7-yl] butanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4104430; BDBM50257999
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(1S,2R,4As,5R,6S,8aS)-1,6-bis(1,3-dithiolan-2-yl)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,4a-dimethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-ol
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4102764; BDBM50257952
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
Methyl (1S,2R,4aR,5S,6S,8aS)-2-acetyloxy-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,4a-dimethylspiro[3,4,5,7,8,8a-hexahydro-2H-naphthalene-6,2'-oxirane]-1-carboxylate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4092762; BDBM50258010
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]acetyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143286
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[3] | |||
| Compound Name |
[(2R,4As,5S,6S,8aS)-5-[(E)-2-[5-(3-fluorophenyl)pyridin-2-yl]ethenyl]-1,1,4a,6-tetramethyl-2,3,4,5,6,7,8,8a-octahydronaphthalen-2-yl] butanoate
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL4086105; BDBM50257973
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[5] | |||
| Compound Name |
N-[(2S)-1-[[(2S)-1-[[(2S)-1-Amino-1-oxo-3-phenylpropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[(1S)-2-(4-fluorophenyl)-1-[[2-(methylamino)acetyl]amino]ethyl]-1,3-thiazole-4-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL296793; BDBM50070660
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 100000 nM
|
[2] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2R)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL336277; BDBM50031393
Click to Show/Hide
|
||||
| Activity |
EC50 = 109300 nM
|
[6] | |||
| Compound Name |
(3R)-N-[(2S)-1-[[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]-3,4-dihydro-1H-isoquinoline-3-carboxamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL2370955; BDBM50454448
Click to Show/Hide
|
||||
| Activity |
EC50 = 110000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-pyridin-3-ylpropanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143315
Click to Show/Hide
|
||||
| Activity |
EC50 = 116000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2R)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-4-[bis(dimethylamino)methylideneamino]butanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143279
Click to Show/Hide
|
||||
| Activity |
IC50 = 140000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-5-aminopentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143255
Click to Show/Hide
|
||||
| Activity |
IC50 = 141000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl(pyridin-3-yl)amino]-3-(4-fluorophenyl)propanoyl]amino]-3-[4-(diaminomethylideneamino)phenyl]propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143292
Click to Show/Hide
|
||||
| Activity |
IC50 ~ 160000 nM
|
[3] | |||
| Compound Name |
(S)-2-{(S)-2-[(S)-2-((S)-2-Amino-3-hydroxy-propionylamino)-3-phenyl-propionylamino]-4-methyl-pentanoylamino}-4-methyl-pentanoic acid amide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL132939; BDBM50031404
Click to Show/Hide
|
||||
| Activity |
EC50 = 185000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-3-[4-(diaminomethylideneamino)phenyl]-2-[[(2S)-3-(4-fluorophenyl)-2-(thiophen-2-ylsulfonylamino)propanoyl]amino]propanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143305
Click to Show/Hide
|
||||
| Activity |
IC50 = 193000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-Acetamido-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL445632; BDBM50031419
Click to Show/Hide
|
||||
| Activity |
EC50 = 200000 nM
|
[6] | |||
| Click to Show/Hide the Information of All Poor Binders | |||||
| Non Binders of This Target (in total, 28 non binders) | Download | Top | |||
|---|---|---|---|---|---|
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-3-(4-aminophenyl)-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL337852; BDBM50031408
Click to Show/Hide
|
||||
| Activity |
EC50 = 235000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-N,4-dimethylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL335264; BDBM50031388
Click to Show/Hide
|
||||
| Activity |
EC50 = 260000 nM
|
[6] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-chlorophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143318
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2R)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-4-phenylbutanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143300
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-methoxyphenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143269
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[3] | |||
| Compound Name |
(2S)-2-[[(2S)-2-[[(2S)-2-[Acetyl-[(E)-3-phenylprop-2-enoyl]amino]-3-(4-fluorophenyl)propanoyl]amino]-3-(4-nitrophenyl)propanoyl]amino]-N-[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL3143316
Click to Show/Hide
|
||||
| Activity |
IC50 > 300000 nM
|
[3] | |||
| Compound Name |
(2S)-N-[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]-methylamino]-4-methylpentanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340389; BDBM50031409
Click to Show/Hide
|
||||
| Activity |
EC50 = 350000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL132307; BDBM50031389
Click to Show/Hide
|
||||
| Activity |
EC50 = 400000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[(2-amino-2-methylpropanoyl)amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL337674; BDBM50031415
Click to Show/Hide
|
||||
| Activity |
EC50 = 415000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2R)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL134820; BDBM50031429
Click to Show/Hide
|
||||
| Activity |
EC50 = 500000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-(2,3,4,5,6-pentafluorophenyl)propanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL129730; BDBM50031378
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methyl-2-[[(2S)-2-[[(2S)-2-(methylamino)propanoyl]amino]-3-phenylpropanoyl]amino]pentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL339157; BDBM50031391
Click to Show/Hide
|
||||
| Activity |
EC50 = 600000 nM
|
[6] | |||
| Compound Name |
(2S)-2-[[(2S)-2-(4-Aminobutanoylamino)-3-phenylpropanoyl]amino]-N-[(2S)-1-[[(2S)-1-amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL337273; BDBM50031396
Click to Show/Hide
|
||||
| Activity |
EC50 = 730000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-amino-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL433847; BDBM50031410
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
Fllrdpqdk-NH2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL406548; BDBM50031384
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2R)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL335036; BDBM50031428
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]-methylamino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL335915; BDBM50031394
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-4-phenylbutanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL131738; BDBM50031387
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-2-phenylacetyl]amino]-4-methylpentanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL132128; BDBM50031400
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2R)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130226; BDBM50031418
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[6] | |||
| Compound Name |
(S)-3-Amino-N-((S)-1-{(S)-1-[(S)-1-((S)-1-carbamoyl-4-guanidino-butylcarbamoyl)-3-methyl-butylcarbamoyl]-3-methyl-butylcarbamoyl}-2-phenyl-ethyl)-succinamic acid
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130307; BDBM50031411
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]propanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL130335; BDBM50031412
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-3-[4-(aminomethyl)phenyl]-2-[[(2S)-2-aminopropanoyl]amino]propanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL340043; BDBM50031385
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]-methylamino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-aminopropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL132254; BDBM50031390
Click to Show/Hide
|
||||
| Activity |
EC50 = 800000 nM
|
[6] | |||
| Compound Name |
L-Phenylalaninamide, L-seryl-
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL337394; ZINC2243060; BDBM50031416; (S)-2-Amino-N-((S)-1-carbamoyl-2-phenyl-ethyl)-3-hydroxy-propionamide
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
Ac-SFLLRDPQDK-NH2
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL415138; BDBM50031379
Click to Show/Hide
|
||||
| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2R)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-3-hydroxypropanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
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|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL133618; BDBM50031423
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| Activity |
EC50 > 800000 nM
|
[6] | |||
| Compound Name |
(2S)-N-[(2S)-1-[[(2S)-1-Amino-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-phenylpropanoyl]amino]-4-methylpentanamide
Click to Show/Hide
|
Investigative | Compound Info | ||
| Synonyms |
CHEMBL338639; BDBM50031433
Click to Show/Hide
|
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| Activity |
EC50 > 1200000 nM
|
[6] | |||
| Click to Show/Hide the Information of All Non Binders | |||||
| References | Top | ||||
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| REF 1 | Solid-phase parallel synthesis applied to lead optimization: Discovery of potent analogues of the GPIIb/IIIa antagonist RWJ-50042. Bioorg Med Chem Lett. 1996 Oct 22;6(20):2371-6. | ||||
| REF 2 | Thrombin receptor (PAR-1) antagonists. Heterocycle-based peptidomimetics of the SFLLR agonist motif. Bioorg Med Chem Lett. 1998 Jul 7;8(13):1649-54. | ||||
| REF 3 | Development of potent thrombin receptor antagonist peptides. J Med Chem. 1996 Dec 6;39(25):4879-87. | ||||
| REF 4 | Heterocycle-peptide hybrid compounds. Aminotriazole-containing agonists of the thrombin receptor (PAR-1). Bioorg Med Chem Lett. 1999 May 17;9(10):1423-8. | ||||
| REF 5 | Discovery of Potent Orally Active Protease-Activated Receptor 1 (PAR1) Antagonists Based on Andrographolide. J Med Chem. 2017 Aug 24;60(16):7166-7185. | ||||
| REF 6 | Development of a potent thrombin receptor ligand. J Med Chem. 1995 Sep 29;38(20):4125-30. | ||||
| REF 7 | Characterization of Protease-Activated Receptor (PAR) ligands: Parmodulins are reversible allosteric inhibitors of PAR1-driven calcium mobilization in endothelial cells. Bioorg Med Chem. 2018 May 15;26(9):2514-2529. | ||||
| REF 8 | Photoactivatable peptides based on BMS-197525: a potent antagonist of the human thrombin receptor (PAR-1). Bioorg Med Chem Lett. 1999 Jan 18;9(2):279-84. | ||||
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